Romiplostim for Management of Refractory Immune Thrombocytopenic Purpura in the Immediate Postpartum Period

Author Department

Nephrology; Medicine

Document Type

Article, Peer-reviewed

Publication Date

5-2020

Abstract

We present a case of a pregnant woman with chronic immune thrombocytopenic purpura and chronic hypertension who developed pre-eclampsia with severe features warranting delivery. Her overall clinical picture and liver enzymes improved in the immediate postpartum period, however, aggressively progressing thrombocytopenia posed a diagnostic dilemma to the interdisciplinary care team. After failing to respond to first-line therapies including high-dose corticosteroids and intravenous immunoglobulin, she was successfully managed with a trial of the thrombopoietin receptor agonist, Romiplostim.

PMID

32430352

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