Using Breast Milk to Assess Breast Cancer Risk: The Role of Mass Spectrometry-Based Proteomics
Author Department
PVLSI
Document Type
Article, Peer-reviewed
Publication Date
7-2014
Abstract
Although mammography and treatment advances have led to declines in breast cancer mortality in the United States, breast cancer remains a major cause of morbidity and mortality. Breast cancer in young women is associated with increased mortality and current methods of detecting breast cancers in this group of women have known limitations. Tools for accurately assessing personal breast cancer risk in young women are needed to identify those women who would benefit the most from earlier intervention. Proteomic analysis of breast milk could identify biomarkers of breast cancer risk and provide a tool for identifying women at increased risk. A preliminary analysis of milk from four women provides a proof of concept for using breast milk to assess breast cancer risk.
Recommended Citation
Schneider SS, Aslebagh R, Wetie AG, Sturgeon SR, Darie CC, Arcaro KF. Using Breast Milk to Assess Breast Cancer Risk: The Role of Mass Spectrometry-Based Proteomics. Adv Exp Med Biol. 2014;806:399-408.