Comparing drug effectiveness at health plans: The ethics of cluster randomized trials

Author Department

Pediatrics

Document Type

Article, Peer-reviewed

Publication Date

9-1-2008

Abstract

"Cluster randomized trials," in which groups of patients are randomly assigned to different therapeutic interventions, provide a powerful way of evaluating drugs. CRTs have not been widely used, in good part because of concerns about whether patients must give informed consent to participate in them. A better understanding of how CRTs fit into clinical practice resolves the concerns.

Publication ISSN

0278-2715

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