Underlying mechanisms of pharmacology and toxicity of a novel PPAR agonist revealed using rodent and canine hepatocytes.

Author Department

Medicine

Document Type

Article, Peer-reviewed

Publication Date

4-1-2007

Abstract

Marked species-specific responses to agonists of the peroxisome proliferator-activated alpha receptor (PPAR alpha) have been observed in rats and dogs, two species typically used to assess the potential human risk of pharmaceuticals in development. In thi

Publication ISSN

0884-8734

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