Major depression and PTSD in pregnant smokers enrolled in Nicotine Gum Treatment Trial.
Author Department
Ob/Gyn
Document Type
Article, Peer-reviewed
Publication Date
1-2013
Abstract
BACKGROUND AND OBJECTIVES:
Pregnant women face considerable barriers to smoking cessation. The purpose of this study was to determine the prevalence of major depressive disorder (MDD) and post-traumatic stress disorder (PTSD) and response to smoking cessation treatment in pregnant smokers participating in a randomized, placebo-controlled trial of nicotine gum.
METHODS:
Participants were 194 low-income, ethnically diverse pregnant smokers.
RESULTS:
Utilizing a structured interview, 45% and 18% of the subjects met criteria for a lifetime diagnosis of MDD and PTSD, respectively. There was no difference in response to treatment, based on the presence of either of these psychiatric disorders.
CONCLUSIONS:
Cumulatively, these findings provide evidence of the high degree of unmet mental health needs in pregnant smokers.
SCIENTIFIC SIGNIFICANCE:
Pregnant women with a history of MDD and PTSD appear to be as likely to benefit from smoking cessation treatment as those without such a history.
Recommended Citation
Dornelas E, Oncken C, Greene J, Sankey HZ, Kranzler HR. Major depression and PTSD in pregnant smokers enrolled in Nicotine Gum Treatment Trial. Am J Addict. 2013 Jan;22(1):54-9.
