A case of diffuse panbronchiolitis caused by Mycoplasma amphoriforme

Author Department

Pulmonary/Critical Care Medicine; Surgery; Pathology; Medicine

Document Type

Article, Peer-reviewed

Publication Date

5-2023

Abstract

Mycoplasma amphoriforme is a novel specie which was discovered in 2003 and associated with congenital immune deficiency. It has been described as an underlying cause of bronchopneumonia. There is limited description of the in vitro sensitivities. In this article, we present the first description of M. amphoriforme as the causative agent of diffuse panbronchiolitis in a patient with X-linked hypogammaglobulinema and bronchiectasis, with symptoms improved by treatment with azithromycin. We also describe the difficulty obtaining this organism through routine culture and the need to consider culture independent methods of recovery when the suspicion is high.

Keywords: Bronchiectasis; Chronic bronchial suppurative diseases; Congenital immunodeficiency.

PMID

37285647

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