nPercutaneous Coronary Intervention Versus Coronary Artery Bypass Surgery for Unprotected Left Main Coronary Disease: G-LM Registry
Author Department
Cardiology; Medicine
Document Type
Article, Peer-reviewed
Publication Date
9-2021
Abstract
Coronary artery bypass surgery (CABG) has been the standard of care for revascularization for patients with obstructive unprotected left main coronary disease (ULMCA). There have been multiple randomized and registry data demonstrating the technical and clinical efficacy of PCI in certain patients with ULMCA. The purpose of this study is to evaluate clinical outcomes of ULMCA PCI as compared to CABG in patients requiring revascularization in three Gulf countries. All ULMCA cases treated by PCI with DES versus CABG were retrospectively identified from 14 centers in 3 Arab Gulf countries (KSA, UAE, and Bahrain) from January 2015 to December 2019. In total, 2138 patients were included: 1222 were treated with PCI versus 916 with CABG. Patients undergoing PCI were older, and had higher comorbidities and mean European System for Cardiac Operative Risk Evaluation (EuroSCORE). Aborted cardiac arrest and cardiogenic shock were reported more in the PCI group at hospital presentation. In addition, lower ejection fractions were reported in the PCI group. In hospital mortality and major adverse cardiovascular and cerebrovascular events (MACCE) occurred more in patients undergoing CABG than PCI. At median follow-up of 15 months (interquartile range, 30), no difference was observed in freedom from revascularization, MACCE, or total mortality between those treated with PCI and CABG. While findings are similar to Western data registries, continued follow-up will be needed to ascertain whether this pattern continues into latter years.
Recommended Citation
Daoulah A, Alasmari A, Hersi AS, Alshehri M, Garni TA, Abuelatta R, Amin H, Almahmeed W, Aljohar A, Abumelha BK, Alzahrani B, Ghani MA, Yousif N, Hashmani S, Salem MAl-Faifi, Kazim HM, Refaat W, Dahdouh Z, Khaliel F, Aithal J, Elmahrouk A, Ibrahim AM, Elganady A, Qutub MA, Alama MN, Abohasan A, Hassan T, Balghith M, Alqahtani AM, Abdelaziz AF, Altnji I, Hussien AF, Abdulhabeeb IAM, Ahmad O, Haddara MM, Alqahtani AH, Alshahrani SS, Qenawi W, Izzeldin MH, El-Sayed O, Jamjoom A, Moghairi AA, Amri HA, Ibrahim WM, Alarbash MM, Hussain T, Shamsi F, Selim E, Ramadan M, Al-Sergani H, Mohamed T, Khalifa AA, Hiremath N, Ibrahim AAT, Abdallah H, Elprince A, Diab A, Seoud DEA, Alghamdi AA, Alebrahim KE, Basudan D, Nasser FOMA, Ali IAA, Shawky AM, Ghonim AA, Khushail AA, Feteih MN, Abualnaja S, Alhaddadi B, Alhamid S, Ahmed WA, Jafary ZM, Ahnia S, Gasem J, Alaydarous S, Khatab T, Mohamed A, Maghrabi M, Samadi FA, Kannout TH, Mahrous N, Almaleh Y, Riyami ABA, Altayyeb Y, Ahmed MA, Ahmed RA, Tawfik W, Almegreb N, Faden MS, Haq E, AlOtaibi SN, Eldesoky A, Clarkson FA, Lotfi A. nPercutaneous Coronary Intervention Versus Coronary Artery Bypass Surgery for Unprotected Left Main Coronary Disease: G-LM Registry. Curr Probl Cardiol. 2021 Sep 26:101002. doi: 10.1016/j.cpcardiol.2021.101002. Epub ahead of print.
PMID
34587490