Choriocarcinoma in an AIDS patient: Relapsing but not fatal
Medicine; Ob/Gyn; Pathology
Choriocarcinoma is associated with high mortality in immunocompromised patients, in contrast to a good prognosis in immunocompetent individuals. Respiratory failure due to metatstatic choriocarcinoma is associated with high mortality in any patient. We report a case of a woman with AIDS that survived metastatic choriocarcinoma and respiratory failure. We also observed that in contrast to some in vitro studies, the markedly elevated levels of beta-subunit of human chorionic gonadotropin in this patient did not have any apparent inhibitory effect on viral replication.
Shah AM, Tidswell M, Prefontaine M, Skiest DJ, Pantanowitz L. Choriocarcinoma in an AIDS patient: Relapsing but not fatal Int J STD AIDS 2008 Jul;19(7):496-8.