Title

Bronchial thermoplasty: State of the art

Author Department

Pulmonary/Critical Care Medicine

Document Type

Article, Peer-reviewed

Publication Date

6-2022

Abstract

Since the publication of a sham-controlled, randomized trial (AIR2) and subsequent marketing approval by the US Food and Drug Administration, we have significantly advanced our understanding of bronchial thermoplasty (BT)'s scientific basis, long-term safety, clinical efficacy and cost-effectiveness. In particular, the last 2 years have witnessed multiple research publications on several of these counts. In this review, we critically appraise our evolving understanding of BT's biologic underpinnings and clinical impact, offer an evidence-based patient workflow guide for the busy pulmonologist and highlight both current challenges as well as potential solutions for the researcher and the clinician.

Keywords: bronchial thermoplasty; cost-effectiveness; efficacy; mechanism of action; safety; severe asthma.

PMID

35692074

Share

COinS