Multisystem Inflammatory Syndrome in an Adult With COVID-19-A Trial of Anakinra: A Case Report
Infectious Diseases; Medicine
COVID-19 disease has been a pandemic caused by a β-coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A life-threatening multisystem inflammatory syndrome (MIS), secondary to SARS-CoV-2 virus infection, sharing common features with Kawasaki disease shock syndrome, staphylococcal/streptococcal shock syndrome, and macrophage activation syndrome in pediatric patients has been described. A total of 27 cases in adults (MIS-A) with a similar presentation have been reported so far. Here we describe the case of a 21-year-old man admitted with abdominal pain, diarrhea, tachycardia, and low blood pressure. He had elevated troponin, ferritin, and interleukin-2 receptor levels and had evidence of myocarditis. He tested positive for SARS-CoV-2 IgG antibody, and a diagnosis of MIS-A was made. Our case adds to the scant literature on this topic, and to our knowledge, it is the first case where anakinra was administered. He recovered well. MIS-A should be considered when young adults present with multiorgan dysfunction.
Keywords: SARS-CoV-2; multisystem inflammatory syndrome; myocarditis.
Aggarwal A, Cohen E, Figueira M, Sabharwal V, Herlihy JM, Bronwen C, Barnett ED, Pelton SI, Camelo IY. Multisystem Inflammatory Syndrome in an Adult With COVID-19-A Trial of Anakinra: A Case Report. Infect Dis Clin Pract (Baltim Md). 2021 Nov;29(6):e420-e423. doi: 10.1097/IPC.0000000000001028. Epub 2021 May 15.