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Submissions from 2016

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Rhodiola crenulata induces an early estrogenic response and reduces proliferation and tumorsphere formation over time in MCF7 breast cancer cells, Kelly Gregory, Elizabeth Henchey, Jennifer Ser-Dolansky, and Sallie Schneider PhD

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Mechanism of neem limonoids-induced cell death in cancer: Role of oxidative phosphorylation, Nagendra Yadava PhD

Submissions from 2015

Estrogen-mediated signaling is differentially affected by the expression levels of Sfrp1 in mammary epithelial cells, Kelly Gregory and Sallie Schneider PhD

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Genetic modification of human mesenchymal stem cells helps to reduce adiposity and improve glucose tolerance in an obese diabetic mouse model, Chul Kim and Nagendra Yadava PhD

Rhodiola crenulata inhibits Wnt/β-catenin signaling in glioblastoma, Maria Carmen Mora MD, Lotfi Bassa, Kaitlyn Wong MD, Michael Tirabassi MD, Richard Arenas MD, and Sallie Schneider PhD

Curcumin Ingestion Inhibits Mastocytosis and Suppresses Intestinal Anaphylaxis in a Murine Model of Food Allergy, Jennifer Ser-Dolansky and Sallie Schneider PhD

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Oxidative phosphorylation-dependent regulation of cancer cell apoptosis in response to anticancer agents, Nagendra Yadava PhD

Submissions from 2014

SKP2 Overexpression Is Associated With Increased Serine 10 Phosphorylation of p27 (pSer10p27) in Triple-Negative Breast Cancer, Brooke Bentley, Sharon Marconi, Christopher Otis MD, and Sallie Schneider PhD

The effects of diet induced obesity on breast cancer associated pathways in mice deficient in SFRP1, Kelly Gauger and Sallie Schneider PhD

Tumour supressor secreted frizzled related protein 1 regulates p53-mediated apoptosis, Kelly Gauger and Sallie Schneider PhD

DNA methylation in paired breast epithelial and white blood cells from women undergoing reduction mammoplasty, Melissa Johnson MD, D Joseph Jerry, and Sallie Schneider PhD

Comparative Analysis of the Mitochondrial Physiology of Pancreatic β Cells, Chul Kim, Pikeshkumar Patel MD, Melissa Brown, Elizabeth Henchey, and Nagendra Yadava PhD

Using Breast Milk to Assess Breast Cancer Risk: The Role of Mass Spectrometry-Based Proteomics, Sallie Schneider PhD

Tumor-derived mural-like cells coordinate with endothelial cells: role of YKL-40 in mural cell-mediated angiogenesis, Wei Yan, Brooke Bentley, and Rong Shao

Submissions from 2013

Mice deficient in sfrp1 exhibit increased adiposity, dysregulated glucose metabolism, and enhanced macrophage infiltration, Kelly Gauger, Brooke Bentley, and Sallie Schneider PhD

The RhoA pathway mediates MMP-2 and MMP-9-independent invasive behavior in a triple-negative breast cancer cell line, Sallie Schneider PhD, Brooke Bentley, and Christopher Otis MD

Impaired mitochondrial metabolism and mammary carcinogenesis, Nagendra Yadava PhD, Sallie Schneider PhD, D. Joseph Jerry, and Chul Kim

Submissions from 2012

The Parkin-like human homolog of Drosophila ariadne-1 (HHARI) can induce aggresome formation in mammalian cells and is immunologically detectable in Lewy bodies, Brooke Bentley, Chul Kim, Luis Moral MD, and Larry Schwartz

Loss of SFRP1 promotes ductal branching in the murine mammary gland, Kelly Gauger, Giovanna Crisi MD, and Sallie Schneider PhD

The novel lupus antigen related protein acheron enhances the development of human breast cancer, Rong Shao, Stephan Scully, Wei Yan, Brooke Bentley, James Mueller MD, Lauren Schwartz MD, and Larry Schwartz

Submissions from 2011

Breast cancer expression of YKL-40 correlates with tumour grade, poor differentiation, and other cancer markers, Richard Arenas MD, Rong Shao, Q Jackie Cao MD, Brooke Bentley, and Wei Yan

Mitochondrial dysfunction impairs tumor suppressor p53 expression/function, Shannon Compton, Sabyasachi Sen MD, D Joseph Jerry, Sallie Schneider, and Chul Kim

In tumors Salmonella migrate away from vasculature toward the transition zone and induce apoptosis, Sabha Ganai MD, Richard Arenas MD, Brooke Bentley, and Neil Forbes

SFRP1 reduction results in an increased sensitivity to TGF-â signaling, Sallie Schneider and Kelly Gauger

Depot-specific adipose weight and gene expression is modulated by myostatin and activin, Sabyasachi Sen MD and Alan Schneyer

Inhibitory activity of YKL-40 in mammary epithelial cell differentiation and polarization induced by lactogenic hormones: A role in mammary tissue involution, Wei Yan, Stephan Scully, Brooke Bentley, Q Jackie Cao MD, and Rong Shao

Submissions from 2010

Pathways contributing to development of spontaneous mammary tumors in BALB/c-Trp53+/- mice, Richard Arenas MD, Christopher Otis MD, Q Jackie Cao MD, and D Joseph Jerry

Dragon enhances BMP signaling and increases transepithelial resistance in kidney epithelial cells, Alan Schneyer

Emerging roles for the TGFbeta family in pancreatic beta-cell homeostasis, Alan Schneyer

First-trimester follistatin-like-3 levels in pregnancies complicated by subsequent gestational diabetes mellitus, Alan Schneyer

Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research, Alan Schneyer

The follistatin-288 isoform alone is sufficient for survival but not for normal fertility in mice, Alan Schneyer

Acheron, a Lupus antigen family member, regulates integrin expression, adhesion, and motility in differentiating myoblasts, Larry Schwartz

GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition, Rong Shao, Wei Yan, Q Jackie Cao MD, Richard Arenas MD, and Brooke Bentley

Submissions from 2009

Prenylated Rab acceptor domain family member 1 is involved in stimulated ACTH secretion and inhibition, Shannon Compton

Tumour-targeted delivery of TRAIL using Salmonella typhimurium enhances breast cancer survival in mice, Sabha Ganai MD, Richard Arenas MD, and Neil Forbes

Down-regulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44high/cd24low population which is invasive and resistant to anoikis, Kelly Gauger, Sallie Schneider, and Melissa Troester

Detection and differentiation of normal, cancerous, and metastatic cells using nanoparticle-polymer sensor arrays, D Joseph Jerry

Activation of host wound responses in breast cancer microenvironment, Sallie Schneider, Melissa Troester, and D Joseph Jerry

The biology of activin: recent advances in structure, regulation and function, Alan Schneyer

Iron oxide nanoparticles induce human microvascular endothelial cell permeability through reactive oxygen species production and microtubule remodeling, Rong Shao

YKL-40, a secreted glycoprotein, promotes tumor angiogenesis, Rong Shao, Q Jackie Cao MD, Richard Arenas MD, Brooke Bentley, and Wei Yan

Submissions from 2008

Bacterial therapies: completing the cancer treatment toolbox, Neil Forbes

Integrating cell-cycle progression, drug penetration and energy metabolism to identify improved cancer therapeutic strategies, Neil Forbes

Tumor-targeted delivery of TRIAL using Salmonella typhimurium enhances breast cancer survival, Sabha Ganai MD, Richard Arenas MD, and Neil Forbes

Estrogen and progesterone induce persistent increases in p53-dependent apoptosis and suppress mammary tumors in BALB/c-Trp53+/- mice, D Joseph Jerry

Protein-passivated Fe3O4 nanoparticles: Low toxicity and rapid heating for thermal therapy, D Joseph Jerry

Insulin-like growth factor-I inhibits growth regulatory responses engaged by estrogen and progesterone in the mouse mammary gland, Sallie Schneider

Rhodiola crenulata induces death and inhibits growth of breast cancer cell lines, Sallie Schneider

Transcriptional responses to estrogen and progesterone in mammary gland identify networks regulating p53 activity, Sallie Schneider and D Joseph Jerry

Differential antagonism of activin, myostatin and GDF11 by wild type and mutant follistatin, Alan Schneyer

The structure of FSTL3.activin A complex: Differential binding of N-terminal domains influences follistatin-type antagonist specificity, Alan Schneyer

Atrophy and programmed cell death of skeletal muscle, Larry Schwartz

Cell death in myoblasts and muscles, Larry Schwartz and Honor Glenn

Distinct Angiogenic Mediators Are Required for Basic Fibroblast Growth Factor- and Vascular Endothelial Growth Factor-induced Angiogenesis: The Role of Cytoplasmic Tyrosine Kinase c-Abl in Tumor Angiogenesis, Rong Shao, Wei Yan, and Brooke Bentley

EGFR associated expression profiles vary with breast tumor subtype, Melissa Troester

Submissions from 2007

Engineered strategies to overcome therapeutic resistance in solid tumors., Neil Forbes

Flux analysis shows that hypoxia-inducible-factor-1-alpha minimally affects intracellular metabolism in tumor spheroids, Neil Forbes

Mathematical model of tumor metabolism and therapeutic efficacy based on mass balance, transport phenomena and reaction kinetics, Neil Forbes

Salmonella typhimurium lacking ribose chemoreceptors localize in tumor quiescence and induce apoptosis, Neil Forbes

Targeting bacteriolytic therapy of solid tumors using salmonella typhimurium, Neil Forbes, Richard Arenas MD, Sabha Ganai MD, and Brooke Bentley

Mammary tumor modifiers in BALB/cJ mice heterozygous for p53., D Joseph Jerry

Roles for estrogen and progesterone in breast cancer prevention, D Joseph Jerry

Activation of the tumor suppressor gene p53 is higher in normal parous human breast tissue than the nulliparous counterpart, D Joseph Jerry, Sallie Schneider, and Giovanna Crisi MD

Activin subunit and receptor expression in normal and cleft human fetal palate tissues, Alan Schneyer

FSTL3 deletion reveals roles for TGF-beta family ligands in glucose and fat homeostasis in adults, Alan Schneyer

Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) Type II receptors by BMP2 and BMP4, Alan Schneyer

Acheron, a novel member of the lupus antigen family, is induced during the programmed cell death of skeletal muscles in the moth Manduca sexta, Larry Schwartz

Induction of Anoikis following myoblast transplantation into SCID mouse muscles requires the Bit1 and FADD pathways, Larry Schwartz

Differential roles of HIC-5 isoforms in the regulation of cell death and myotube formation during myogenesis, Larry Schwartz and Honor Glenn

Common genetic variation in GATA-binding protein 3 and differential susceptibility to breast cancer by estrogen receptor alpha tumor status, Melissa Troester

Submissions from 2006

Charge-dependent cellular uptake and tissue penetration of gold nanoparticles, Neil Forbes

Estradiol stimulates the biosynthetic pathways of breast cancer cells: Detection by metabolic flux analysis, Neil Forbes

Glutathione-mediated delivery and release using monolayer protected nanoparticle carriers, Neil Forbes

Incorporating cell cycle progression and drug penetration into metabolic models of multicellular tumor spheroid growth, Neil Forbes

Incorporating energy metabolism into a growth model of multicellular tumor spheroids, Neil Forbes

Light-regulated release of DNA and its delivery to nuclei by means of photolabile gold nanoparticles, Neil Forbes

Microfluidic devices for the assembly and culture of three-dimensional multi-cellular constructs with diffusion-limited microenvironments, Neil Forbes

Profile of a bacterial tumor killer, Neil Forbes

Salmonella typhimurium specifically chemotax and proliferate in heterogeneous tumor tissue in vitro, Neil Forbes

Using chemical engineering to develop cancer therapeutics, Neil Forbes

The role of secreted frizzled-related protein in parityinduced protection against breast cancer, Sallie Schneider

Cellular retinol binding protein-1 (CRBP1) is up-regulated in response to parity-induced changes in the mammary gland, Sallie Schneider and D Joseph Jerry

Transcriptional responses to estrogen and progesterone in mammary gland identify a role for extracellular matrix in modulating p53, Sallie Schneider and D Joseph Jerry

Transduction of a mesenchyme-specific gene periostin into 293T cells induces cell invasive activity through epithelial-mesenchymal transformation, Rong Shao and Wei Yan

Submissions from 2005

In situ characterization of cell cycle distribution of multicellular spheroid as a drug delivery model, Neil Forbes

Quantifying the metabolism of cancerous and non-cancerous breast cancer cells: Implications for drug target identification, Neil Forbes

Using engineering to characterize and overcome multidrug resistance in solid human tumors, Neil Forbes

Targeting bacteriolytic therapy of solid tumors using salmonella typhimurium, Neil Forbes, Richard Arenas MD, and Sabha Ganai MD

Activation of p53, inhibition of telomerase activity and induction of estrogen receptor beta are associated with the anti-growth effects of combination of ovarian hormones and retinoids in immortalized human mammary epithelial cells, Sallie Schneider

Sensitivity to DNA damage is a common component of hormone based strategies for protection of the mammary gland, Sallie Schneider

Notch1 expression in benign and malignant mammary epithelium, Sallie Schneider and Giovanna Crisi MD

Sensitivity to DNA damage is a common component of hormone-based strategies for protection of the mammary gland., Sallie Schneider and D Joseph Jerry

The effect of Insulin-like Growth Factor-I on parity induced protection against breast cancer, Sallie Schneider, D Joseph Jerry, and Brooke Pazik

Identification and analysis of Hic-5/ARA55 isoforms: Implications for integrin signaling and steroid hormone action, Larry Schwartz

Programmed cell death in insect neuromuscular systems during metamorphosis, Larry Schwartz

Submissions from 2004

Incorporating cellular metabolism into growth models of multicellular tumor spheroids, Neil Forbes

USANS as a probe of large-scale structure in attractive colloidal glasses of block copolymer micelles, Neil Forbes

Loss of heterozygosity occurs via mitotic recombination in Trp53+/- mice and associates with mammary tumor susceptibility of the BALB/c strain., Christopher Otis MD and D Joseph Jerry

Human microvascular endothelial cells immortalized with human telomerase catalytic protein: a model for the study of in vitro angiogenesis, Rong Shao