Sensitivity to DNA damage is a common component of hormone-based strategies for protection of the mammary gland.

Author Department

PVLSI

Document Type

Article, Peer-reviewed

Publication Date

8-1-2005

Abstract

An early full-term pregnancy significantly reduces the risk of getting breast cancer in women. In animals, this protection can be mimicked by a short-term exposure to physiologic doses of estrogen plus progesterone. Sensitization of p53 and up-regulation

Publication ISSN

0003-2999

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