Title

Major depression and PTSD in pregnant smokers enrolled in Nicotine Gum Treatment Trial.

Author Department

Ob/Gyn

Document Type

Article, Peer-reviewed

Publication Date

1-2013

Abstract

BACKGROUND AND OBJECTIVES:

Pregnant women face considerable barriers to smoking cessation. The purpose of this study was to determine the prevalence of major depressive disorder (MDD) and post-traumatic stress disorder (PTSD) and response to smoking cessation treatment in pregnant smokers participating in a randomized, placebo-controlled trial of nicotine gum.

METHODS:

Participants were 194 low-income, ethnically diverse pregnant smokers.

RESULTS:

Utilizing a structured interview, 45% and 18% of the subjects met criteria for a lifetime diagnosis of MDD and PTSD, respectively. There was no difference in response to treatment, based on the presence of either of these psychiatric disorders.

CONCLUSIONS:

Cumulatively, these findings provide evidence of the high degree of unmet mental health needs in pregnant smokers.

SCIENTIFIC SIGNIFICANCE:

Pregnant women with a history of MDD and PTSD appear to be as likely to benefit from smoking cessation treatment as those without such a history.

Share

COinS